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A 10-day wait reduces tirzepatide to approximately 25% of peak levels

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Last year, the drugmaker submitted an application for approving tirzepatide for the treatment of HFpEF and obesity to the European Medicines Agency (EMA) and plans to submit it to other regulatory agencies soon.

This means that drawing the same number of units from a 20mg/mL vial delivers double the dose compared to a 10mg/mL vial

[53] In two of these (NCT03954834 and NCT04039503), participants were randomly assigned to receive either tirzepatide or placebo injection weekly

Although retatrutide is showing promising results in clinical trials, it has not yet been FDA approved, so conclusions cant be made around it being the best weight loss solution