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The findings suggest that GLP-1s may deliver meaningful improvements in both disease severity and patient-reported quality of life

Participants continued losing weight throughout 48-68 week studies without needing dose increases

Our articles on Insulin Resistance Explained, Postprandial Glucose Dysregulation, and HOMA-IR and Insulin Resistance explore these connections in more detail

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Setting realistic expectationsexplaining that maximum benefits may take 3 months to manifest and that gastrointestinal side effects typically improve with timeenhances treatment persistence and patient satisfaction with this therapeutic approach

This is consistent with data from other randomized trials targeting cardiovascular outcomes, and a 12-month Phase II randomized trial in adults with mild cognitive impairment