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Notably, improvements in reproductive dysfunction have been observed in several animal models of polycystic ovary syndrome (PCOS), including enhanced follicular development, normalized estrous cycles, and reversal of polycystic ovarian morphology (Singh et al., 2019

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Expression of StAR and subsequently increased progesterone synthesis could be modulated by upregulation of ERK activity (189, 190)

A network meta-analysis examining 105 randomized controlled trials with 219,283 participants found no significant association between GLP-1 receptor agonists as a class and increased infection risk, including UTIs

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GLP-1 supports mental wellness by restoring microbial balance and improving satiety signalling, potentially reducing emotional eating and cravings (Singh et al, 2024)