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Description
Neuroprogression happens

Common clinical findings in these cases include: Persistent nausea and early satiety lasting weeks or months after discontinuation of the drug

Preclinical and clinical studies have uncovered several gastrointestinal effects of metformin, including stimulation of the incretin hormone glucagon-like peptide-1 (GLP-1) [8], slowing of gastric emptying [8], suppression of intestinal glucose absorption [9], inhibition of bile acid resorption [10, 11] and modulation of the gut microbiota [12]

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September 3, 2024

The severity is usually less intense than the initial onset, and the duration of adjustment is shorter