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My take: GLP-1RAs may become more than metabolic drugs, but oncology needs prospective cancer-outcome data before calling this prevention

It can vary

A rise in the use of non-FDA-approved diabetes and obesity medications has spurred health care professionals and medical organizations to speak out about safety concerns.In December, the FDA released a statement to health care professionals and patients warning against the use of compounded and counterfeit versions of diabetes and obesity drugs, including semaglutide (Ozempic/Wegovy, Novo

This newly charted pathway - separate from previously described mechanisms that broadly affect appetite - could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder

Lifestyle and individual factors also play a role.

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