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GLP-1 and GIP/GLP-1 medications significantly slow gastric emptying, which can affect the absorption of oral medications, including oral estrogen or progesterone formulations

Medications include compounded semaglutide and tirzepatide (503B pharmacy), brand-name Wegovy and Zepbound with PA support, and non-GLP-1 alternatives (topiramate, bupropion, metformin, orlistat) if you are ineligible

If you experience severe or persistent headaches, consult your GP or prescriber

These symptoms need medical attention and should not be ignored

P = .001) and 6 months (7.2% vs