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This means no more time-consuming trips to the pharmacy, more consistency in your treatment, and ultimately more peace of mind

However, when combined with insulin or sulfonylureas in research models of diabetes, hypoglycemia risk increases and dose adjustments of background therapies are typically recommended

Clear cold-chain/shipping protocols: Some injectable medications, such as GLP-1 drugs, must remain cold during shipping

Differences in receptor binding and pharmacodynamics could explain this observation, but further investigation is needed to determine whether the differences stem from drug properties, population characteristics or both. The authors also disclosed their inability to establish causality for the association between semaglutide and ocular AEs, noting that the biological mechanisms remain unclear

Insurers, for their part, blame the situation on the two pharmaceutical giants that dominate the GLP-1 market: Eli Lilly and Novo Nordisk

doi:10.1016/S2468-1253(23)00068-7 Knudsen LB, Lau J