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however, the rarity of SIS events and the wide uncertainty of effect size (although null, effect may be compatible with a risk as high as threefold) calls for a cautious interpretation of our results

Still, the long-term effects of using GLP-1RA and SGLT-2i together were unclear
Confusion about this drives many purchasing mistakes

The biggest gap: understanding The most consistent insight wasnt the changes themselves

August 6, 2025:S2468-6530(25)00355-0
The same neurological pathways that adapted to the stimulant adapt back when the stimulant is removed
