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Furthermore, other pathophysiological abnormalities [5], such as increased renal glucose re-absorption [6] and the diminished incretin effect [7] have been found to contribute to the hyperglycemia manifested by the disease

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7 In particular, weight loss induced by GLP-1 RAs has been associated with significant improvement in debilitating headaches, especially in conditions such as idiopathic intracranial hypertension (IIH) and migraine, both of which are known to be exacerbated by obesity and its associated systemic inflammation

Specific measures like safety, effectiveness, and dosing for AUD still need to be tested and confirmed

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