lantus and glp 1 glp-1_analogs [TUSOM GLP-1: Actions on Beta-cell Mass

Investigators reported that improvements in reproductive markers appeared earlier than anticipated, prompting the publication of preliminary findings before completion of the larger study

Were here to guide and support

pylori in patients with peptic ulcer disease (395)

fast 20262029 pipeline snapshot: Novo Nordisk CagriSema (GLP-1 + amylin) Filing 2026 Lilly Orforglipron (oral GLP-1) + Retatrutide (triple agonist) Launch window 20262027 Amgen Maritide (GLP-1 + GIP) 20272028 target BI / Zealand Survodutide (GLP-1 + glucagon) 2027 Altimmune Pemvidutide (GLP-1 + glucagon) 2027 Roche CT-388 / Petrelintide possible 2029 And one notable miss: Pfizer Danuglipron discontinued Clear trend: Single GLP-1 dual triple agonists Competition is shifting from: Who has a GLP-1? to Who has the most effective combination biology? Execution risk is still real but the bar for efficacy is moving quickly

Gut issues are a big concern with higher doses

Getting Started: Your First Steps Before diving into the details, heres what you should do right now if youre planning pregnancy: Stop GLP-1 after coordinating with your prescribing doctor (plan for 2-3 months before trying to conceive) Start prenatal vitamins today (400-800mcg folic acid) Switch to more reliable birth control if youre on pills (consider IUD or barrier methods) Schedule a preconception visit with your OB/GYN Start tracking cycles (app or paper) Write down your GLP-1 details (drug, dose, last injection date) Understanding the Pregnancy Safety Concerns Before diving into timelines and action plans, lets establish why this matters and what we actually knowversus what were still learning