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GLP-1 and Ca 2+ Induced Ca 2+ Release Once Ca 2+ enters the -cell, it plays several roles in insulin secretion

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This helps increase insulin secretion and slows gastric emptying, which means your stomach takes longer to empty its contents, helping you feel full longer and eat less

doi: 10.1001/jama.2020.2298

Gastrointestinal effects remain the most common complaint

The phentermine versus semaglutide comparison and the phentermine versus GLP-1 analysis explain why incretin-based therapies have largely superseded older appetite suppressants in clinical practice