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In particular, glucagon has firmly been demonstrated to enhance hepatic lipid metabolism, Hepatic GCGR agonism leads to upregulation of lipid catabolism pathways in the hepatocyte where a number of key regulatory transporters and enzymes facilitate beta oxidation of fatty acids (61)

Heart Rate: Glucagon agonism can transiently increase the heart rate

2022;5(9):e2232584

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Rationale, strengths, and limitations of real-world evidence in oncology: a Canadian review and perspective