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Bupropion ignores serotonin almost entirely and instead focuses on two other neurotransmitters that play critical roles in mood, motivation, and energy: dopamine and norepinephrine

Luo Z, Chou OH-I, Ng ZMW et al (2023) Compare SGLT2I versus non-SGLT2I users in type-2 diabetic mellitus patients on GLP-1 receptor agonist: a population-based and machine learning causal inference analysis

Prespecified outcomes The primary outcome is all-cause mortality

Some patients achieve target weight loss at lower doses, while others require maximum dosing for optimal results

CNO dose-dependently attenuated cocaine seeking in hM3D(Gq)-expressing rats (Fig 2G)

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