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16 Tirzepatide concentrations and exposure metrics (area under the curve [AUC] and maximum plasma concentration [ C max ]) were simulated for virtual trial participants using final model estimates for fixed effects and random effects, and observed demographic variables (body weight, BMI, and sex)

*Recognize that current evidence supports the overall ocular safety of semaglutide but does not definitively rule out rare but serious complications

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Both semaglutide and tirzepatide can cause gastrointestinal side effects: nausea, vomiting, diarrhoea, and stomach discomfort

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