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Description
GLP-1 is able to stimulate cAMP formation in RIN 1046-38 cells, which in turn causes an increase in insulin mRNA levels and insulin release, and insulin accumulation in the culture fluid was observed by adding GLP-1 (7-37) to RIN 1046-38 cells for 1 h incubation (Drucker et al., 1987)
Am J Hypertens 27(1):130139 Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, Simpson JA, Drucker DJ (2013) GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
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Understanding these transitions helps you anticipate what your cells need before symptoms become crises
