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Anton Bilchik, MD, PhD, surgical oncologist, chief of medicine, and director of the Gastrointestinal and Hepatobiliary Program at Providence Saint Johns Cancer Institute in Santa Monica, CA, who was also not involved in this study, agreed

Exendin-4 has been shown to act on the Wnt/-catenin pathway in osteoblasts via the GLP-1R, thereby promoting bone formation and reducing sclerostin levels in T2DM rats (Kim et al., 2013)

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Athauda D, Gulyani S, Karnati HK, Li Y, Tweedie D, Mustapic M, et al

We therefore carried out RNA-seq analysis using dissected intestines from the sterile glp-1(-) , fem-3(-) , and mog-3(-) mutant strains and compared to the WT