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Clinical Trial Data: STEP-1 Study Results The STEP-1 (Semaglutide Treatment Effect in People with Obesity) trial remains the gold standard for understanding semaglutide weight loss results

ICP was recorded with the MPR-1 monitor (Raumedic) in a standardized supine position as previously described

Greater weight loss may occur, especially if patients begin to feel full, eat less, and exercise

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Under the brand name Ozempic, semaglutide is currently approved for reducing cardiovascular risk in type 2 diabetes patients with at least one diagnosed cardiovascular comorbidity [9]

These outcomes are in agreement with previous experiments, suggesting that diabetes-aggravated ischemic damage was resulting from multifactorial interactions and normalization of hyperglycemia alone is not the major mechanism of neuroprotective effects