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doi: 10.1056/NEJMoa220860

Schwartz Hypothalamic and hindbrain neurocircuits that regulate food intake and energy expenditure in response to input from the adipocyte hormone leptin.

Efficacy Results: Treatment with BYDUREON 2 mg once weekly (QW) resulted in mean HbA1c reduction that was statistically significantly greater compared to sitagliptin 100 mg/day

However, as the drug concentration falls, you may notice a temporary return of symptoms that the medication was controlling

Bariatric surgery has been shown to be very successful in obesity management but medical weight management solutions are needed for those individuals that either are not candidates for surgery or are seeking non-surgical alternatives