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Semaglutide was the first GLP-1RA to meet the primary endpoint in a phase II NASH trial

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The researchers found that, over a mean follow-up of 31.8 months, glucose-lowering therapy was not significantly associated with reduced cognitive impairment or dementia (OR = 0.83

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of 28 studies involving 304,060 individuals with 481 documented aspiration cases found that GLP-1 RA exposure was not associated with increased pulmonary aspiration (odds ratio 1.04, 95% confidence interval 0.871.25) despite a significant association with retained gastric contents (odds ratio 5.96, 95% confidence interval 3.968.98) [38]

The science of transdermal GLP-1 delivery Let us set aside the specific product for a moment and ask a fundamental question