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Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial

not a maintenance dose) Weeks 58: 5 mg once weekly Then: consider +2.5 mg increments (e.g., 7.5 10 12.5 15 mg) no sooner than every 4 weeks, if appropriate and tolerated Maintenance target: 5 mg, 10 mg, or 15 mg once weekly, chosen by your clinician based on response and side effects This gradual approach is designed to reduce the risk of gastrointestinal (GI) side effects during dose changes and allow time to evaluate how youre doing at each step

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After the slowdown during the pandemic, the agency has ramped up its global oversight again, and the data tells a clear story

What Happens if You Use Expired Tirzepatide