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an encounter or billing diagnosis with ICD-10-CM O*): Between 12 months before the first reading through 9 months after the follow-up reading Evidence of amputation during baseline or outcome measurements for weight outcome Censoring First of: Measurement closest to 12 months

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It is extracted primarily from chicory root through hot water extraction, followed by purification and spray drying

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It is noteworthy that hybrids GG2[D u A u A u ] 9,10,11,12 ( 2 , 13 nM) and GG2[F u I u A u ] 22,23,24,25 ( 16 , 62 nM) which contain native side chains and shifted substitution pattern still preserve substantial affinity with GLP-1R, although with over a hundred fold loss compared to the native peptide