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As such, these agents are generally contraindicated in patients with a personal or family history of MTC and in patients with multiple endocrine neoplasia syndrome type 2 (MEN2)

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These reactions were observed in clinical trials: Abdominal distension Abdominal pain Acute gallbladder disease Acute kidney injury Acute pancreatitis Allergic reactions Constipation Diarrhea Dizziness Dyspepsia (indigestion) Eructation (burping) Fatigue Flatulence Gastroenteritis Gastroesophageal reflux disease Headache Hypoglycemia (in diabetic patients) Nasopharyngitis (cold) Nausea Thyroid C-cell tumors Vomiting Studies, consumer reports and lawsuits have highlighted other side effects of semaglutide medications

However, it typically takes about 8-12 weeks of consistent use to reach healthy blood sugar levels

Melena (black faeces) often indicates stomach bleeding, for example a bleeding stomach ulcer