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Description
73 Fewer studies have evaluated the risk of biliary disease, possibly due to impaired gallbladder emptying, 74 however, tirzepatide was shown to portend an increased risk (RR 1.97, 95% CI 1.143.42, I2 = 0.0%, p = 0.558)

The most common motivation is convenience and comfort: injections require weekly self-administration and sometimes refrigeration, which can feel inconvenient or uncomfortable for some individuals, especially those who dislike needles or managing cold storage

Miller, M

Compared to before intervention, the percentage of weight loss in all doses of cagrilintide group patients after intervention was significantly higher than that in the placebo group patients (6.0% -10.8% vs

This often results in persistent vomiting and hospitalization, and can cause long-term health consequences

wrote the first draft
