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Oh, S.-H., Lee, S

Specific tissue types, including the brain and kidney, do not need insulin for glucose intake because the constitutive expression of the GLUT1 and GLUT3 transporters exists in these tissues [1]

doi: 10.1016/j.neuroscience.2010.08.028 218 MaTDuXPickJESuiGBrownleeMKlannE

Physiological Integration of Taste and Metabolism

* These therapies are not FDA approved for the treatment, cure, or prevention of any disease

In the 2022 SURMOUNT-1 study published in NEJM, three doses of tirzepatide were compared with placebo (1:1:1:1) to determine effects on percent weight change over the course of 72 weeks