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Early research suggests that retatrutide may provide even greater weight loss and metabolic benefits than semaglutide or tirzepatide

doi:10.1007/s00125-017-4379-x [9] Aroda, V

Effects of GLP-1 Analogues and Agonists on the Gut Microbiota: A Systematic Review

Dosage and Treatment Length Most patients start with a lower dose and gradually increase it based on tolerance and progress

The decrease in expression in response to high glucose levels was reversed by the presence of GLP-1 [83]

The retatrutide phase 2 body-composition substudy showed lean-mass loss in line with the total weight loss, without evidence of the medication causing extra lean mass losses