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For weight management, only semaglutide (Wegovy) and liraglutide (Saxenda) are specifically licensed in the UK, with access typically through specialist weight management services according to NICE criteria

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NICE Clinical Guideline CG184 on dyspepsia and GORD recommends a stepwise approach to management and sets out criteria for urgent and routine referral based on alarm features

Tirzepatide can complement these lifestyle modifications, providing individuals with the tools to achieve sustainable weight loss and maintain long-term glycemic control

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