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In addition to its local gut functions, the gut microbiota also produces bioactive metabolites, such as short-chain fatty acids (SCFAs), lipopolysaccharides (LPS), secondary bile acids, and generates precursors of uremic toxins, targeting systemic distant organs such as the liver, kidney, and cardiovascular system [5, 6]

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By 2030, 35% of US households will include a GLP-1 user

The negative control group received blank PLGA MNs (without semaglutide), a positive control group also referred to as injection group, received the semaglutide via injections (each injection was provided every 7 days Fig

376,380 The therapeutic effects of PF1801 are primarily achieved by modulating several key proteins that play central roles in inflammation and cellular metabolism