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They are not suitable for everyone, including some patients with certain endocrine, pancreatic, gastrointestinal, kidney, pregnancy-related, or medication-related considerations

By week 48, most had reached a plateau, though this plateau occurred at dramatically lower body weights than their starting points

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Taking NSAIDs with food and discussing gastroprotection with your GP is sensible

These early-stage side effects tend to peak around day 35 and rarely last longer than a full week without improvement