new glp 1 receptor agonists agonist In the ATTAIN-1 phase 3, randomized trial, the use of orforglipron, Frontiers | GLP-1 Receptor Agonists:

GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d

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Although, in the last 10 years, the use of GLP-1 RAs, especially semaglutide and liraglutide, has increased, its clinical implications and how it affects metabolic parameters have yet to be fully consolidated

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Aims/hypothesis Tirzepatide is a novel dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) currently under review for marketing approval