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Individual tolerability varies significantly and requires close clinical follow-up

Many patients starting GLP-1 medications like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) wonder about this symptom

GLP-1 injections are part of incretin-based therapies

Exercise regularly: Physical activity boosts GLP-1 secretion and insulin sensitivity

Early evidence suggests GLP-1s may reduce chronic inflammation and improve cellular function, supporting heart, liver, kidney, and brain health, and potentially lowering risk for obesity-related cancers

In two analyses of spontaneous reports from the US Food and Drug Administrations adverse event reporting system database, the reporting rates of thyroid cancer were 4.7 and 8 times higher, respectively, for GLP1 receptor agonists compared with other diabetes drugs.23 In a meta-analysis based on 15 clinical trials that included at least one thyroid cancer outcome event, the odds ratio for thyroid cancer associated with GLP1 receptor agonists was 1.49 (95% confidence interval 0.83 to 2.66)