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In preliminary findings from preclinical studies, concurrent therapy with GLP-1RAs and SGLT-2is may change intestinal microbial biology in distinctive or synergistic ways

Do not switch on your own your prescribing physician should manage the changeover to avoid dosing errors or a gap in treatment

CONTRAVE is not recommended for use in patients with end-stage renal disease [see Dosage and Administration (2.2) and Clinical Pharmacology (12.3)]

These injuries have resulted in significant physical and emotional trauma, impacting their quality of life

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Cette approche est certes moins spectaculaire et moins facilement mdiatisable que les annonces tonitruantes qui accompagnent les dcouvertes de thrapies innovantes, mais elle est indispensable