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Comparative risk of incident malignancies in rheumatoid arthritis patients treated with Janus kinase inhibitors or bDMARDs: observational data from the German RABBIT register

Sehgal P, Lichtenstein GR, Khanna T, et al

28 This analysis was based on four trials reporting change in total cholesterol and high-density lipoprotein and five trials reporting change in triglycerides

Tesamorelin effects are less immediately obvious

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This means retatrutide may look promising, but it is still too early to say that its safety profile is fully established