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Remember that whilst Mounjaro reduces appetite, adequate nutrition remains essentialsevere food restriction is neither necessary nor advisable

For example, certain FTO variants are linked to reduced satiety signaling, meaning patients with these markers may need slightly higher protein intake or more frequent small meals to maintain fullness on tirzepatide

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Risk differences were attenuated among metformin monotherapy users (2.0 and 4.1) compared with users of 2 or more diabetes medications (5.7 and 4.0) versus SGLT2is and DPP4is, respectively