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Nausea, vomiting, generalized weakness, and abdominal pain were the predominant symptoms reported
Whether this is a direct action of metformin on GLP-1 release, and whether some of the glucose-lowering effect of metformin occurs ...
Glucagon-like peptides (GLP-1 and GLP-2) are two proglucagon-derived intestinal hormones that mediate distinct physiological functions through two related receptors (GLP-1R and GLP-2R) which are important drug targets for metabolic disorders and Crohns disease, respectively
Conclusion GLP-1 RA use was associated with substantially reduced all-cause death but a small increased risk of acute pancreatitis, particularly during early treatment

Even Halle Berry agrees.
