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Diabetes Care 32 , 8490 (2009)

Inter- and intrasubject variability of solid and liquid gastric emptying parameters

In health, GLP-1 stimulates the synthesis and secretion of insulin from pancreatic -cells in a glucose-dependent manner (i.e., it is activated when blood glucose levels are elevated, typically in the postprandial state)

This substance works similarly to a naturally occurring hormone in the body called GLP-1, which is released from the intestines after eating

[1] Orforglipron is also chemically different from previous oral GLP-1s

GLP-1 receptor agonist use does not increase risk of respiratory complications post-endoscopy