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Yokote, K

tirzepatide 4813.45 Da Conclusion# Tirzepatide and retatrutide represent successive generations of incretin-based therapeutics

Diabetes Care 33(2):428433 Eguchi Y, Kitajima Y, Hyogo H, Takahashi H, Kojima M, Ono M et al (2015) Pilot study of liraglutide effects in non-alcoholic steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J)

no significant sex-specific differences

Glucagon-like peptide-1 receptor agonist liraglutide inhibits endothelin-1 in endothelial cell by repressing nuclear Factor-kappa B activation

Consistent with earlier studies, side effects emerged as the most commonly cited reason for discontinuation, regardless of medication indication
