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They do so through a mechanism that is different than stimulants such as caffeine, which can elevate heart rate, feel jittery, and cause energy crashes

doi: 10.1056/EVIDoa2200014 51 GaddeKMAllisonDBRyanDHPetersonCATroupinBSchwiersMLet al
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This value was used to calculate (tau/Ka) values through normalization of the transduction coefficient (tau/Ka) for each ligand in each signalling pathway to the reference ligand (hGLP1 in black) and the reference signalling pathway (cAMP)

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