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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for managing type 2 diabetes and, more recently, approved for weight management

All compounded medications are dispensed under licensed provider prescriptions through licensed compounding pharmacies

1 The incretin effect was termed when researchers noted that individuals had a greater secretion of insulin following an oral glucose challenge as opposed to IV glucose administration

Data from bariatric surgery, which achieves weight loss by alteration of appetite hormones including GLP-1, suggest that significant weight loss may benefit the mother but be detrimental for the offspring with an increased risk of small for gestational age offspring and preterm delivery [73, 74]

Liraglutide (Saxenda) was one of the earlier forms of longer-lasting GLP-1s and reduces HbA1c (average blood glucose) levels by around 1.3% on average and fasting plasma glucose by 2 mmol/L

Nausea is another frequently reported gastrointestinal side effect