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Leavens, PhD , can be reached at [email protected].

STEP UP: higher dose exploration The STEP UP trial investigated a higher dose of 7.2 mg weekly, three times the standard 2.4 mg dose

Importantly, the metabolic and behavioral abnormalities observed in male BBS5 / mice were recapitulated in females (Supplemental Figure 1, DJ), suggesting that there were no sex differences in disease manifestation

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Lee, Y.-M