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Description
The FDA-approved prescribing information for Mounjaro (tirzepatide for diabetes) does not list anger or irritability as recognized adverse effects

Berard LD, Siemens R, Woo V
Kingma, D
Kyrou, I

158,159 However, there is a lack of safety data for younger age groups, and earlier studies reported a prevalence of 0.73.3% in this population

This can increase intestinal permeability temporarily, which contributes to bloating, cramping, and the general digestive unease users report