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Clinical implication: clinicians should treat vaginal symptoms in patients taking semaglutide as real and addressable , but approach causality cautiously: prioritise common diagnoses (genitourinary syndrome of menopause, infections, dermatologic vulvar disease, STIs, irritant/contact dermatitis, pelvic floor disorders), identify important confounders (notably SGLT2 inhibitors, antibiotics, hormonal therapies), manage symptoms and underlying conditions, and report suspected adverse reactions when there is a reasonable temporal relationship and alternative causes are less likely

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For localized relief, you can try calamine lotion or a cold compress

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Metformin Alternatives Due to Diarrhea The following classes of diabetes medication have lower rates of diarrhea and may be suitable replacements, though each comes with its own profile of side effects and costs