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A natural decline in overall caloric interest or minor dry mouth, which can be effortlessly managed with consistent daily hydration

Glucagon-like peptide-1 receptor agonists (GLP-1RA) have shown potent metabolic benefits in type 2 diabetes (T2D) and obesity, but their efficacy and safety in CS remain unexplored

![Figure][1] Graphical Abstract: ### Competing Interest Statement The FR + FMG laboratory receives funding from AstraZeneca, Eli Lilly and LGM for unrelated research and FMG consults for Kallyope (New York)

Learn why GLP-1 medications like Wegovy and Zepbound cause digestive side effects in 19-30% of patients, plus expert strategies to manage symptoms and when to contact your doctor.
