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The Trump administration announced a pricing model for popular GLP-1 drugs used to treat type 2 diabetes and obesity

Physicians may prescribe compounded medications as needed to meet patient requirements or address drug shortages

64% at 1 year and 84% at 2 years in those without diabetes Risk factors of discontinuation include lower income, older age, lower weight loss, cost, among others

This landmark policy change recognises obesity as a chronic disease and recommends that GLP-1 antagonists are used by adults for the long-term treatment of obesity

Learn the criteria for coverage and how to check whether you qualify for Zepbound coverage.

Conclusions Differences in manufacturing processes affect chemical/physical stability and impurity profile, and may impact immunogenicity