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Phentermine and GLP-1 receptor agonists are distinct medications that work through different biological pathways to support weight loss

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The AAP previously recommended it.

The experimental data indicate GLP-1 and its analogs to have direct effects on the cardiovascular system, in addition to their classic glucoregulatory actions

Aims/hypothesis A protective role of sodiumglucose cotransporter 2 inhibitors (SGLT2is) and glucagon-like peptide 1 receptor agonists (GLP1-ra) in the development of diabetic retinopathy and diabetic macular oedema has been described in some recent studies, which may extend beyond glycaemic control