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Description
To increase the plasma half-life by avoiding renal elimination, GLP-1 analogs were modified by adding acyl groups (liraglutide and semaglutide) or large molecules such as albumin (albiglutide) and the Fc portion of IgG (dulaglutide)
Levi, J
It is important to note that there is no definitive evidence establishing a permanent taste alteration with GLP-1 therapy, and individual experiences vary considerably

During 72 weeks of treatment, people taking tirzepatide at doses of 5, 10, or 15 mg lost an average of 15.0%, 19.5%, and 20.9%, respectively, compared with just 3.1% in people taking a placebo

Weight loss with Ozempic doses used for type 2 diabetes is typically more modest
Your healthcare provider will need to identify alternative treatment strategies for diabetes management or weight loss
