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Description
Whilst not currently licensed for PCOS in the UK, growing evidence suggests GLP-1 therapy may address both metabolic and reproductive features of this complex condition
In conclusion, retatrutide exhibits strong efficacy for improving glucose levels and promoting weight loss in patients with diabetes, obesity and CKD, displaying a distinctive dose-response pattern where lower doses may be more effective for glycemic control

It acts on both GLP-1 and GIP receptors, compared to semaglutides single GLP-1 action
"Medicaid Coverage of and Spending on GLP-1s." kff.org State Medicaid policy documents: NC Medicaid, CA DHCS, NH Medicaid, MI Public Radio NovoCare

They're prescribed for type 2 diabetes management, chronic weight management, and increasingly for cardiovascular risk reduction
doi: 10.1161/01.HYP.26.3.460
