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No definitive studies exist, but case reports suggest this may be a real issue

En estudios comparativos, ha superado a agonistas del receptor GLP-1 populares, como la semaglutida y la dulaglutida, tanto en el control glucmico como en la reduccin de peso

Tirzepatide lowers hunger levels and changes how the stomach empties

Vitamin B12 deserves particular attention, as both metformin (often co-prescribed with tirzepatide) and reduced animal product intake can affect B12 status

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Tirzepatide as adjunct to insulin in adults with type 1 diabetes and overweight or obesity shows the most consistent signal for body weight reduction, with possible improvements in HbA1c and insulin requirements