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Arabinoxylan-oligosaccharide caused a decrease in early postprandial GLP-1 accompanied by a decrease in alpha diversity and an increase in fecal Bifidobacterium , Akkermansia , and Lactobacillus (81)

GLP-1 receptor deficiency in the diabetic nephropathy-resistant C57BL/6-Akita mouse contributes to the development of diabetic nephropathy, and liraglutide treatment suppressed the progression of nephropathy of the KK/Ta-Akita mouse, which shows high susceptibility to diabetic nephropathy [14], suggesting that GLP-1 action might play an important role in prevention of diabetic nephropathy

Using databases from the US Department of Veterans Affairs, researchers at the Washington University School of Medicine in St

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The molecule is currently undergoing a Phase 2 clinical study for obesity and type 2 diabetes (NCT05669599), with research findings expected to be updated by the end of 2024