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This is a distinguishing factor from the traditional, secretagogue class of drugs used in the treatment of Type 2 DM, which are not glucose-dependent and therefore carry a risk of hypoglycemia

FIGURE 7 The study was repeated using the same rat model to compare responses to 10, 25 and 50 g semaglutide applied to the intestinal surface versus 10-fold lower doses applied via the i.v

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Most people experience some degree of slowed gastric emptying, but the extent and clinical impact vary widely

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