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Clinical trial participants reported improved sleep patterns after the adjustment period, with 73% noting better overall rest quality by week 12

If dose adjustment is needed, it is preferable to use the appropriate strength tablet rather than attempting to modify the existing tablets

100:4059-4066 [PMC free article: PMC4702444] [PubMed: 26305617] 125

Because retatrutide is dose-escalated gradually in trial protocols, participants who are unable to tolerate higher doses due to side effects may not achieve the same degree of weight loss as those who reach the target maintenance dose

Gglucagon-like peptide-1 analogue liraglutide (Saxenda): mechanism of action, efficacy for the treatment of obesity